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A Case of Gastric Adenocarcinoma in a Shih Tzu Dog: Successful Treatment of Early Gastric Cancer

A 9-year-old castrated male Shih Tzu dog was referred to us, because of chronic vomiting. The patient’s hematological, radiographic, ultrasonographic, endoscopic and histological examinations were evaluated for diagnosis. Hematologic analysis indicated moderate anemia and azotemia. Based on the imag...

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Autores principales: LEE, Hee-Chun, KIM, Ji-Hyun, JEE, Cho-Hee, LEE, Jae-Hoon, MOON, Jong-Hyun, KIM, Na-Hyun, SUR, Jung-Hyang, CHO, Kyu-Woan, KANG, Byeong-Teck, HA, Jeongim, JUNG, Dong-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143645/
https://www.ncbi.nlm.nih.gov/pubmed/24646602
http://dx.doi.org/10.1292/jvms.13-0315
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author LEE, Hee-Chun
KIM, Ji-Hyun
JEE, Cho-Hee
LEE, Jae-Hoon
MOON, Jong-Hyun
KIM, Na-Hyun
SUR, Jung-Hyang
CHO, Kyu-Woan
KANG, Byeong-Teck
HA, Jeongim
JUNG, Dong-In
author_facet LEE, Hee-Chun
KIM, Ji-Hyun
JEE, Cho-Hee
LEE, Jae-Hoon
MOON, Jong-Hyun
KIM, Na-Hyun
SUR, Jung-Hyang
CHO, Kyu-Woan
KANG, Byeong-Teck
HA, Jeongim
JUNG, Dong-In
author_sort LEE, Hee-Chun
collection PubMed
description A 9-year-old castrated male Shih Tzu dog was referred to us, because of chronic vomiting. The patient’s hematological, radiographic, ultrasonographic, endoscopic and histological examinations were evaluated for diagnosis. Hematologic analysis indicated moderate anemia and azotemia. Based on the imaging studies, an oval-shaped mass was identified in the gastric pylorus area. A proliferative mass was found on endoscopic examination, and we performed biopsy using grasping forceps. The histopathological findings of the biopsy specimens indicated hypertrophic gastritis, and Y-U pyloroplasty was performed. However, histopathological examination of the surgically resected mass revealed tubular adenocarcinoma of the stomach. Then, carboplatin chemotherapy was performed 4 times for 13 weeks. Clinical signs, such as vomiting, were resolved gradually after surgery and chemotherapy, and the patient’s condition was managed favorably until recently (30 months after surgery). This case report describes clinical features, imaging studies, endoscopic characteristics and histopathological and immunohistochemical features of gastric tubular adenocarcinoma as early gastric cancer in a dog.
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spelling pubmed-41436452014-08-26 A Case of Gastric Adenocarcinoma in a Shih Tzu Dog: Successful Treatment of Early Gastric Cancer LEE, Hee-Chun KIM, Ji-Hyun JEE, Cho-Hee LEE, Jae-Hoon MOON, Jong-Hyun KIM, Na-Hyun SUR, Jung-Hyang CHO, Kyu-Woan KANG, Byeong-Teck HA, Jeongim JUNG, Dong-In J Vet Med Sci Internal Medicine A 9-year-old castrated male Shih Tzu dog was referred to us, because of chronic vomiting. The patient’s hematological, radiographic, ultrasonographic, endoscopic and histological examinations were evaluated for diagnosis. Hematologic analysis indicated moderate anemia and azotemia. Based on the imaging studies, an oval-shaped mass was identified in the gastric pylorus area. A proliferative mass was found on endoscopic examination, and we performed biopsy using grasping forceps. The histopathological findings of the biopsy specimens indicated hypertrophic gastritis, and Y-U pyloroplasty was performed. However, histopathological examination of the surgically resected mass revealed tubular adenocarcinoma of the stomach. Then, carboplatin chemotherapy was performed 4 times for 13 weeks. Clinical signs, such as vomiting, were resolved gradually after surgery and chemotherapy, and the patient’s condition was managed favorably until recently (30 months after surgery). This case report describes clinical features, imaging studies, endoscopic characteristics and histopathological and immunohistochemical features of gastric tubular adenocarcinoma as early gastric cancer in a dog. The Japanese Society of Veterinary Science 2014-03-20 2014-07 /pmc/articles/PMC4143645/ /pubmed/24646602 http://dx.doi.org/10.1292/jvms.13-0315 Text en ©2014 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Internal Medicine
LEE, Hee-Chun
KIM, Ji-Hyun
JEE, Cho-Hee
LEE, Jae-Hoon
MOON, Jong-Hyun
KIM, Na-Hyun
SUR, Jung-Hyang
CHO, Kyu-Woan
KANG, Byeong-Teck
HA, Jeongim
JUNG, Dong-In
A Case of Gastric Adenocarcinoma in a Shih Tzu Dog: Successful Treatment of Early Gastric Cancer
title A Case of Gastric Adenocarcinoma in a Shih Tzu Dog: Successful Treatment of Early Gastric Cancer
title_full A Case of Gastric Adenocarcinoma in a Shih Tzu Dog: Successful Treatment of Early Gastric Cancer
title_fullStr A Case of Gastric Adenocarcinoma in a Shih Tzu Dog: Successful Treatment of Early Gastric Cancer
title_full_unstemmed A Case of Gastric Adenocarcinoma in a Shih Tzu Dog: Successful Treatment of Early Gastric Cancer
title_short A Case of Gastric Adenocarcinoma in a Shih Tzu Dog: Successful Treatment of Early Gastric Cancer
title_sort case of gastric adenocarcinoma in a shih tzu dog: successful treatment of early gastric cancer
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143645/
https://www.ncbi.nlm.nih.gov/pubmed/24646602
http://dx.doi.org/10.1292/jvms.13-0315
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