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Accounting for relatedness in family-based association studies: application to Genetic Analysis Workshop 18 data
In the last few years, a bewildering variety of methods/software packages that use linear mixed models to account for sample relatedness on the basis of genome-wide genomic information have been proposed. We compared these approaches as implemented in the programs EMMAX, FaST-LMM, Gemma, and GenABEL...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143672/ https://www.ncbi.nlm.nih.gov/pubmed/25519407 http://dx.doi.org/10.1186/1753-6561-8-S1-S79 |