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Comparing the power of family-based association tests for sequence data with applications in the GAW18 simulated data
We apply a family-based extension of the sequence kernel association test (SKAT) to 93 trios extracted from the 20 pedigrees in the Genetic Analysis Workshop 18 simulated data. Each extracted trio includes a unique set of parents to ensure conditionally independent trios are sampled. We compare the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143708/ https://www.ncbi.nlm.nih.gov/pubmed/25519316 http://dx.doi.org/10.1186/1753-6561-8-S1-S27 |