Evaluation of the power and type I error of recently proposed family-based tests of association for rare variants

Until very recently, few methods existed to analyze rare-variant association with binary phenotypes in complex pedigrees. We consider a set of recently proposed methods applied to the simulated and real hypertension phenotype as part of the Genetic Analysis Workshop 18. Minimal power of the methods...

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Detalles Bibliográficos
Autores principales: Hainline, Allison, Alvarez, Carolina, Luedtke, Alexander, Greco, Brian, Beck, Andrew, Tintle, Nathan L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143711/
https://www.ncbi.nlm.nih.gov/pubmed/25519321
http://dx.doi.org/10.1186/1753-6561-8-S1-S36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143711/
https://www.ncbi.nlm.nih.gov/pubmed/25519321
http://dx.doi.org/10.1186/1753-6561-8-S1-S36

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