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Evaluation of the power and type I error of recently proposed family-based tests of association for rare variants
Until very recently, few methods existed to analyze rare-variant association with binary phenotypes in complex pedigrees. We consider a set of recently proposed methods applied to the simulated and real hypertension phenotype as part of the Genetic Analysis Workshop 18. Minimal power of the methods...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143711/ https://www.ncbi.nlm.nih.gov/pubmed/25519321 http://dx.doi.org/10.1186/1753-6561-8-S1-S36 |