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Multiphase analysis by linkage, quantitative transmission disequilibrium, and measured genotype: systolic blood pressure in complex Mexican American pedigrees

We apply a multiphase strategy for pedigree-based genetic analysis of systolic blood pressure data collected in a longitudinal study of large Mexican American pedigrees. In the first phase, we conduct variance-components linkage analysis to identify regions that may harbor quantitative trait loci. I...

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Detalles Bibliográficos
Autores principales: Chen, Zhijian, Tan, Kuan-Rui, Bull, Shelley B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143726/
https://www.ncbi.nlm.nih.gov/pubmed/25519311
http://dx.doi.org/10.1186/1753-6561-8-S1-S108