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Collapsing singletons may boost signal for associating rare variants in sequencing study
Advances in next-generation sequencing technology have made it possible to comprehensively interrogate the entire spectrum of genomic variations including rare variants. They may help capture the remaining genetic heritability which has not been fully explained by previous genome-wide association st...
Autores principales: | Wang, Wei, Wei, Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143730/ https://www.ncbi.nlm.nih.gov/pubmed/25519331 http://dx.doi.org/10.1186/1753-6561-8-S1-S50 |
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