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Mixed-effects models for joint modeling of sequence data in longitudinal studies
In this paper, we propose a novel mixed-effects model for longitudinal changes of systolic blood pressure (SBP) over time that can estimate the joint effect of multiple sequence variants on SBP after accounting for familial correlation and the time dependencies within individuals. First we carried o...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143749/ https://www.ncbi.nlm.nih.gov/pubmed/25519347 http://dx.doi.org/10.1186/1753-6561-8-S1-S92 |