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Deep sequencing reveals the eight facets of the influenza A/HongKong/1/1968 (H3N2) virus cap-snatching process

The influenza A virus RNA polymerase cleaves the 5′ end of host pre-mRNAs and uses the capped RNA fragments as primers for viral mRNA synthesis. We performed deep sequencing of the 5′ ends of viral mRNAs from all genome segments transcribed in both human (A549) and mouse (M-1) cells infected with th...

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Detalles Bibliográficos
Autores principales: Sikora, Dorota, Rocheleau, Lynda, Brown, Earl G., Pelchat, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143772/
https://www.ncbi.nlm.nih.gov/pubmed/25154590
http://dx.doi.org/10.1038/srep06181