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Analysis of Genetic Analysis Workshop 18 data with gene-based penalized regression
Under the premise that multiple causal variants exist within a disease gene and that we are underpowered to detect these variants individually, a variety of methods have been developed that attempt to cluster rare variants within a gene so that the variants may gather strength from one another. Thes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143805/ https://www.ncbi.nlm.nih.gov/pubmed/25519325 http://dx.doi.org/10.1186/1753-6561-8-S1-S43 |