Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis

Gliomas are the most common primary tumours affecting the adult central nervous system and respond poorly to standard therapy. Myc is causally implicated in most human tumours and the majority of glioblastomas have elevated Myc levels. Using the Myc dominant negative Omomyc, we previously showed tha...

Descripción completa

Detalles Bibliográficos
Autores principales: Annibali, Daniela, Whitfield, Jonathan R., Favuzzi, Emilia, Jauset, Toni, Serrano, Erika, Cuartas, Isabel, Redondo-Campos, Sara, Folch, Gerard, Gonzàlez-Juncà, Alba, Sodir, Nicole M., Massó-Vallés, Daniel, Beaulieu, Marie-Eve, Swigart, Lamorna B., Mc Gee, Margaret M., Somma, Maria Patrizia, Nasi, Sergio, Seoane, Joan, Evan, Gerard I., Soucek, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143920/
https://www.ncbi.nlm.nih.gov/pubmed/25130259
http://dx.doi.org/10.1038/ncomms5632

Ejemplares similares

Ejemplares similares