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Single-molecule force spectroscopy reveals force-enhanced binding of calcium ions by gelsolin

Force is increasingly recognized as an important element in controlling biological processes. Forces can deform native protein conformations leading to protein-specific effects. Protein–protein binding affinities may be decreased, or novel protein–protein interaction sites may be revealed, on mechan...

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Detalles Bibliográficos
Autores principales: Lv, Chunmei, Gao, Xiang, Li, Wenfei, Xue, Bo, Qin, Meng, Burtnick, Leslie D., Zhou, Hao, Cao, Yi, Robinson, Robert C., Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143929/
https://www.ncbi.nlm.nih.gov/pubmed/25100107
http://dx.doi.org/10.1038/ncomms5623