Understanding functional miRNA–target interactions in vivo by site-specific genome engineering

MicroRNA (miRNA) target recognition is largely dictated by short ‘seed’ sequences, and single miRNAs therefore have the potential to regulate a large number of genes. Understanding the contribution of specific miRNA–target interactions to the regulation of biological processes in vivo remains challe...

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Detalles Bibliográficos
Autores principales: Bassett, Andrew R., Azzam, Ghows, Wheatley, Lucy, Tibbit, Charlotte, Rajakumar, Timothy, McGowan, Simon, Stanger, Nathan, Ewels, Philip Andrew, Taylor, Stephen, Ponting, Chris P., Liu, Ji-Long, Sauka-Spengler, Tatjana, Fulga, Tudor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143950/
https://www.ncbi.nlm.nih.gov/pubmed/25135198
http://dx.doi.org/10.1038/ncomms5640

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