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How wasting is saving: Weight loss at altitude might result from an evolutionary adaptation

At extreme altitude (>5,000 – 5,500 m), sustained hypoxia threatens human function and survival, and is associated with marked involuntary weight loss (cachexia). This seems to be a coordinated response: appetite and protein synthesis are suppressed, and muscle catabolism promoted. We hypothesise...

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Detalles Bibliográficos
Autores principales: Murray, Andrew J, Montgomery, Hugh E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143966/
https://www.ncbi.nlm.nih.gov/pubmed/24917038
http://dx.doi.org/10.1002/bies.201400042