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The dual PI3K/mTOR inhibitor NVP-BEZ235 enhances nab-paclitaxel antitumor response in experimental gastric cancer

Gastric cancer is the second most common cause of cancer-related deaths worldwide. Taxanes have shown therapeutic effects against gastric cancer while also activating the PI3K/mTOR signaling pathway. We investigated the effects of NVP-BEZ235 (BEZ235), a novel dual PI3K/mTOR inhibitor, alone and in c...

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Detalles Bibliográficos
Autores principales:	ZHANG, CHANG-HUA, AWASTHI, NIRANJAN, SCHWARZ, MARGARET A., SCHWARZ, RODERICH E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144025/ https://www.ncbi.nlm.nih.gov/pubmed/24042258 http://dx.doi.org/10.3892/ijo.2013.2099

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