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Regression hidden Markov modeling reveals heterogeneous gene expression regulation: a case study in mouse embryonic stem cells

BACKGROUND: Studies have shown the strong association between histone modification levels and gene expression levels. The detailed relationships between the two can vary substantially due to differential regulation, and hence a simple regression model may not be adequate. We apply a regression hidde...

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Detalles Bibliográficos
Autores principales:	Lee, Yeonok, Ghosh, Debashis, Zhang, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144088/ https://www.ncbi.nlm.nih.gov/pubmed/24884369 http://dx.doi.org/10.1186/1471-2164-15-360

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