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DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia

Background: Schizophrenia is a complex psychiatric disorder with a lifetime morbidity rate of 0.5–1.0%. The pathophysiology of schizophrenia still remains obscure. Accumulating evidence indicates that DNA methylation, which is the addition of a methyl group to the cytosine in a CpG dinucleotide, mig...

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Detalles Bibliográficos
Autores principales: Numata, Shusuke, Ye, Tianzhang, Herman, Mary, Lipska, Barbara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144343/
https://www.ncbi.nlm.nih.gov/pubmed/25206360
http://dx.doi.org/10.3389/fgene.2014.00280

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