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A Simple And Rapid Minicircle DNA Vector Manufacturing System
Minicircle DNA vectors consisting of a circular expression cassette devoid of the bacterial plasmid DNA backbone provides several advantages including sustained transgene expression in quiescent cells/tissues. Their use has been limited by labor-intensive production. We report on a strategy for maki...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144359/ https://www.ncbi.nlm.nih.gov/pubmed/21102455 http://dx.doi.org/10.1038/nbt.1708 |