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K(+) channel gating: C-type inactivation is enhanced by calcium or lanthanum outside
Many voltage-gated K(+) channels exhibit C-type inactivation. This typically slow process has been hypothesized to result from dilation of the outer-most ring of the carbonyls in the selectivity filter, destroying this ring’s ability to bind K(+) with high affinity. We report here strong enhancement...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144669/ https://www.ncbi.nlm.nih.gov/pubmed/25156116 http://dx.doi.org/10.1085/jgp.201411223 |