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A Novel CXCR4-Selective High-Affinity Fluorescent Probe and Its Application in Competitive Binding Assays
[Image: see text] We recently developed a new, rapid, and specific bioassay system that employs a fluorescent probe fabricated from our discovered CXCR4-specific ligand DV1. This new probe sensitively and selectively blocks the binding of native and synthetic ligands to CXCR4 at nanomolar levels, wi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144712/ https://www.ncbi.nlm.nih.gov/pubmed/25058910 http://dx.doi.org/10.1021/bi500500h |