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PhenoFluor: Practical Synthesis, New Formulation, and Deoxyfluorination of Heteroaromatics

[Image: see text] We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluori...

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Detalles Bibliográficos
Autores principales: Fujimoto, Teppei, Becker, Fabian, Ritter, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144717/
https://www.ncbi.nlm.nih.gov/pubmed/25177149
http://dx.doi.org/10.1021/op500121w
Descripción
Sumario:[Image: see text] We report a practical synthesis method of the reagent PhenoFluor on decagram scale, provide a new formulation of PhenoFluor as a toluene solution, which should decrease challenges associated with the moisture sensitivity of the reagent, and expand the substrate scope of deoxyfluorination with PhenoFluor to heteroaromatics.