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Target-Independent Prediction of Drug Synergies Using Only Drug Lipophilicity
[Image: see text] Physicochemical properties of compounds have been instrumental in selecting lead compounds with increased drug-likeness. However, the relationship between physicochemical properties of constituent drugs and the tendency to exhibit drug interaction has not been systematically studie...
Autores principales: | Yilancioglu, Kaan, Weinstein, Zohar B., Meydan, Cem, Akhmetov, Azat, Toprak, Isil, Durmaz, Arda, Iossifov, Ivan, Kazan, Hilal, Roth, Frederick P., Cokol, Murat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144720/ https://www.ncbi.nlm.nih.gov/pubmed/25026390 http://dx.doi.org/10.1021/ci500276x |
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