Amphiphilic Nanoparticles Repress Macrophage Atherogenesis: Novel Core/Shell Designs for Scavenger Receptor Targeting and Down-Regulation

[Image: see text] Atherosclerosis, an inflammatory lipid-rich plaque disease is perpetuated by the unregulated scavenger-receptor-mediated uptake of oxidized lipoproteins (oxLDL) in macrophages. Current treatments lack the ability to directly inhibit oxLDL accumulation and foam cell conversion withi...

Descripción completa

Detalles Bibliográficos
Autores principales: Petersen, Latrisha K., York, Adam W., Lewis, Daniel R., Ahuja, Sonali, Uhrich, Kathryn E., Prud’homme, Robert K., Moghe, Prabhas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144725/
https://www.ncbi.nlm.nih.gov/pubmed/24972372
http://dx.doi.org/10.1021/mp500188g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144725/
https://www.ncbi.nlm.nih.gov/pubmed/24972372
http://dx.doi.org/10.1021/mp500188g

Ejemplares similares