Cargando…

RHEX, a novel regulator of human erythroid progenitor cell expansion and erythroblast development

Ligation of erythropoietin (EPO) receptor (EPOR) JAK2 kinase complexes propagates signals within erythroid progenitor cells (EPCs) that are essential for red blood cell production. To reveal hypothesized novel EPOR/JAK2 targets, a phosphotyrosine (PY) phosphoproteomics approach was applied. Beyond k...

Descripción completa

Detalles Bibliográficos
Autores principales: Verma, Rakesh, Su, Su, McCrann, Donald J., Green, Jennifer M., Leu, Karen, Young, Peter R., Schatz, Peter J., Silva, Jeffrey C., Stokes, Matthew P., Wojchowski, Don M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144737/
https://www.ncbi.nlm.nih.gov/pubmed/25092874
http://dx.doi.org/10.1084/jem.20130624