Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response

Interventional strategies to treat atherosclerosis, such as transluminal angioplasty and stent implantation, often cause vascular injury. This leads to intimal hyperplasia (IH) formation that induces inflammatory and fibroproliferative processes and ultimately restenosis. We show that phosphoinositi...

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Detalles Bibliográficos
Autores principales: Smirnova, Natalia F., Gayral, Stéphanie, Pedros, Christophe, Loirand, Gervaise, Vaillant, Nathalie, Malet, Nicole, Kassem, Sahar, Calise, Denis, Goudounèche, Dominique, Wymann, Matthias P., Hirsch, Emilio, Gadeau, Alain-Pierre, Martinez, Laurent O., Saoudi, Abdelhadi, Laffargue, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144742/
https://www.ncbi.nlm.nih.gov/pubmed/25073791
http://dx.doi.org/10.1084/jem.20131276

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