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Trends in Condom Use and Risk Behaviours after Sexual Exposure to HIV: A Seven-Year Observational Study

OBJECTIVE: We aimed to determine the trends in numbers and percentages of sexually exposed persons to HIV (SE) consulting an ED for post-exposure prophylaxis (PEP), as well as predictors of condom use. STUDY DESIGN: We conducted a prospective-observational study. METHODS: We included all SE attendan...

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Autores principales: Casalino, Enrique, Choquet, Christophe, Leleu, Agathe, Hellmann, Romain, Wargon, Mathias, Juillien, Gaelle, Yazdanpanah, Yazdan, Bouvet, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144812/
https://www.ncbi.nlm.nih.gov/pubmed/25157477
http://dx.doi.org/10.1371/journal.pone.0104350
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author Casalino, Enrique
Choquet, Christophe
Leleu, Agathe
Hellmann, Romain
Wargon, Mathias
Juillien, Gaelle
Yazdanpanah, Yazdan
Bouvet, Elisabeth
author_facet Casalino, Enrique
Choquet, Christophe
Leleu, Agathe
Hellmann, Romain
Wargon, Mathias
Juillien, Gaelle
Yazdanpanah, Yazdan
Bouvet, Elisabeth
author_sort Casalino, Enrique
collection PubMed
description OBJECTIVE: We aimed to determine the trends in numbers and percentages of sexually exposed persons to HIV (SE) consulting an ED for post-exposure prophylaxis (PEP), as well as predictors of condom use. STUDY DESIGN: We conducted a prospective-observational study. METHODS: We included all SE attendances in our Emergency Department (ED) during a seven-year study-period (2006–2012). Trends were analyzed using time-series analysis. Logistic Regression was used to define indicators of condom use. RESULTS: We enrolled 1851 SE: 45.7% reported intercourse without condom-use and 12.2% with an HIV-infected partner. Significant (p<0.01) rising trends were observed in the overall number of SE visits (+75%), notably among men having sex with men (MSM) (+126%). There were rising trends in the number and percentage of those reporting intercourse without condom-use in the entire population +91% (p<0.001) and +1% (p>0.05), in MSM +228% (p<0.001) and +49% (p<0.001), in Heterosexuals +68% (p<0.001) and +10% (p = 0.08). Among MSM, significant rising trends were found in those reporting high-risk behaviours: anal receptive (+450% and +76%) and anal insertive (+l33% and +70%) intercourses. In a multivariate logistic regression analysis, heterosexuals, vaginal intercourse, visit during the night-shift and short time delay between SE and ED visit, were significantly associated with condom-use. CONCLUSION: We report an increasing trend in the number of SE, mainly among MSM, and rising trends in high-risk behaviours and unprotected sexual intercourses among MSM. Our results indicate that SE should be considered as a high-risk population for HIV and sexually transmitted diseases.
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spelling pubmed-41448122014-08-29 Trends in Condom Use and Risk Behaviours after Sexual Exposure to HIV: A Seven-Year Observational Study Casalino, Enrique Choquet, Christophe Leleu, Agathe Hellmann, Romain Wargon, Mathias Juillien, Gaelle Yazdanpanah, Yazdan Bouvet, Elisabeth PLoS One Research Article OBJECTIVE: We aimed to determine the trends in numbers and percentages of sexually exposed persons to HIV (SE) consulting an ED for post-exposure prophylaxis (PEP), as well as predictors of condom use. STUDY DESIGN: We conducted a prospective-observational study. METHODS: We included all SE attendances in our Emergency Department (ED) during a seven-year study-period (2006–2012). Trends were analyzed using time-series analysis. Logistic Regression was used to define indicators of condom use. RESULTS: We enrolled 1851 SE: 45.7% reported intercourse without condom-use and 12.2% with an HIV-infected partner. Significant (p<0.01) rising trends were observed in the overall number of SE visits (+75%), notably among men having sex with men (MSM) (+126%). There were rising trends in the number and percentage of those reporting intercourse without condom-use in the entire population +91% (p<0.001) and +1% (p>0.05), in MSM +228% (p<0.001) and +49% (p<0.001), in Heterosexuals +68% (p<0.001) and +10% (p = 0.08). Among MSM, significant rising trends were found in those reporting high-risk behaviours: anal receptive (+450% and +76%) and anal insertive (+l33% and +70%) intercourses. In a multivariate logistic regression analysis, heterosexuals, vaginal intercourse, visit during the night-shift and short time delay between SE and ED visit, were significantly associated with condom-use. CONCLUSION: We report an increasing trend in the number of SE, mainly among MSM, and rising trends in high-risk behaviours and unprotected sexual intercourses among MSM. Our results indicate that SE should be considered as a high-risk population for HIV and sexually transmitted diseases. Public Library of Science 2014-08-26 /pmc/articles/PMC4144812/ /pubmed/25157477 http://dx.doi.org/10.1371/journal.pone.0104350 Text en © 2014 Casalino et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Casalino, Enrique
Choquet, Christophe
Leleu, Agathe
Hellmann, Romain
Wargon, Mathias
Juillien, Gaelle
Yazdanpanah, Yazdan
Bouvet, Elisabeth
Trends in Condom Use and Risk Behaviours after Sexual Exposure to HIV: A Seven-Year Observational Study
title Trends in Condom Use and Risk Behaviours after Sexual Exposure to HIV: A Seven-Year Observational Study
title_full Trends in Condom Use and Risk Behaviours after Sexual Exposure to HIV: A Seven-Year Observational Study
title_fullStr Trends in Condom Use and Risk Behaviours after Sexual Exposure to HIV: A Seven-Year Observational Study
title_full_unstemmed Trends in Condom Use and Risk Behaviours after Sexual Exposure to HIV: A Seven-Year Observational Study
title_short Trends in Condom Use and Risk Behaviours after Sexual Exposure to HIV: A Seven-Year Observational Study
title_sort trends in condom use and risk behaviours after sexual exposure to hiv: a seven-year observational study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144812/
https://www.ncbi.nlm.nih.gov/pubmed/25157477
http://dx.doi.org/10.1371/journal.pone.0104350
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