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Nitroglycerin Tolerance in Caveolin-1 Deficient Mice

Nitrate tolerance developed after persistent nitroglycerin (GTN) exposure limits its clinical utility. Previously, we have shown that the vasodilatory action of GTN is dependent on endothelial nitric oxide synthase (eNOS/NOS3) activity. Caveolin-1 (Cav-1) is known to interact with NOS3 on the cytopl...

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Detalles Bibliográficos
Autores principales:	Mao, Mao, Varadarajan, Sudhahar, Fukai, Tohru, Bakhshi, Farnaz R., Chernaya, Olga, Dudley, Samuel C., Minshall, Richard D., Bonini, Marcelo G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144835/ https://www.ncbi.nlm.nih.gov/pubmed/25158065 http://dx.doi.org/10.1371/journal.pone.0104101

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