ZO-1 Knockout by TALEN-Mediated Gene Targeting in MDCK Cells: Involvement of ZO-1 in the Regulation of Cytoskeleton and Cell Shape

ZO-1, ZO-2 and ZO-3 are tight junction-associated scaffold proteins that bind to transmembrane proteins of tight junctions and the underlying cytoskeleton. ZO-1 is involved in the regulation of cytoskeletal organization, but its detailed molecular mechanism is less well understood. Gene knockout is...

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Detalles Bibliográficos
Autores principales: Tokuda, Shinsaku, Higashi, Tomohito, Furuse, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144852/
https://www.ncbi.nlm.nih.gov/pubmed/25157572
http://dx.doi.org/10.1371/journal.pone.0104994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144852/
https://www.ncbi.nlm.nih.gov/pubmed/25157572
http://dx.doi.org/10.1371/journal.pone.0104994

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