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Structural Insights of the ssDNA Binding Site in the Multifunctional Endonuclease AtBFN2 from Arabidopsis thaliana
The multi S1/P1 nuclease AtBFN2 (EC 3.1.30.1) encoded by the Arabidopsis thaliana At1g68290 gene is a glycoprotein that digests RNA, ssDNA, and dsDNA. AtBFN2 depends on three zinc ions for cleaving DNA and RNA at 3′-OH to yield 5′-nucleotides. In addition, AtBFN2′s enzymatic activity is strongly gly...
Autores principales: | Yu, Tsung-Fu, Maestre-Reyna, Manuel, Ko, Chia-Yun, Ko, Tzu-Ping, Sun, Yuh-Ju, Lin, Tsai-Yun, Shaw, Jei-Fu, Wang, Andrew H.-J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144908/ https://www.ncbi.nlm.nih.gov/pubmed/25157844 http://dx.doi.org/10.1371/journal.pone.0105821 |
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