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Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions

AIMS: Most of the calcium that activates contraction is released from the sarcoplasmic reticulum (SR) through the ryanodine receptor (RyR). It is controversial whether activators of the RyR produce a maintained increase in the amplitude of the systolic Ca transient. We therefore aimed to examine the...

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Detalles Bibliográficos
Autores principales:	Greensmith, David J., Galli, Gina L.J., Trafford, Andrew W., Eisner, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145011/ https://www.ncbi.nlm.nih.gov/pubmed/24947416 http://dx.doi.org/10.1093/cvr/cvu158

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