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Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer
BACKGROUND: To identify the novel epitopes from the human papillomavirus type 18 E7 which can sensitize PBMCs of four different major HLA class I A allele. METHODS: Twenty-four synthetic overlapping 15-amino acid peptides were screened by measuring the frequency of CD8(+) cytotoxic T lymphocytes (CT...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145224/ https://www.ncbi.nlm.nih.gov/pubmed/25141788 http://dx.doi.org/10.1186/s12967-014-0229-7 |