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An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity

Advanced lung cancer is complicated by skeletal metastases either due to direct extension from adjacent primaries or, more commonly, due to haematogenous dissemination of neoplastic cells. Lumber spine is the most common site for bony metastases in bronchogenic carcinoma. Proximal lone bones, especi...

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Autores principales: Das, Anirban, Pandit, Sudipta, Das, Sibes k., Basuthakur, Sumitra, Das, Somnath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145377/
https://www.ncbi.nlm.nih.gov/pubmed/25184068
http://dx.doi.org/10.1155/2014/636017
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author Das, Anirban
Pandit, Sudipta
Das, Sibes k.
Basuthakur, Sumitra
Das, Somnath
author_facet Das, Anirban
Pandit, Sudipta
Das, Sibes k.
Basuthakur, Sumitra
Das, Somnath
author_sort Das, Anirban
collection PubMed
description Advanced lung cancer is complicated by skeletal metastases either due to direct extension from adjacent primaries or, more commonly, due to haematogenous dissemination of neoplastic cells. Lumber spine is the most common site for bony metastases in bronchogenic carcinoma. Proximal lone bones, especially humerus, are unusual sites for metastases from lung primaries. Small cell and large cell varieties of lung cancer are most commonly associated with skeletal dissemination. It is also unusual that an asymptomatic squamous cell carcinoma of lung presents with painful, soft tissue swelling with osteolytic metastasis of humerus which is reported in our case. Systemic cytotoxic chemotherapy, local palliative radiotherapy, adequate analgesia, and internal fixation of the affected long bone are different modalities of treatment in this advanced stage of disease. But the prognosis is definitely poor in this stage IV disease.
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spelling pubmed-41453772014-09-02 An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity Das, Anirban Pandit, Sudipta Das, Sibes k. Basuthakur, Sumitra Das, Somnath Case Rep Pulmonol Case Report Advanced lung cancer is complicated by skeletal metastases either due to direct extension from adjacent primaries or, more commonly, due to haematogenous dissemination of neoplastic cells. Lumber spine is the most common site for bony metastases in bronchogenic carcinoma. Proximal lone bones, especially humerus, are unusual sites for metastases from lung primaries. Small cell and large cell varieties of lung cancer are most commonly associated with skeletal dissemination. It is also unusual that an asymptomatic squamous cell carcinoma of lung presents with painful, soft tissue swelling with osteolytic metastasis of humerus which is reported in our case. Systemic cytotoxic chemotherapy, local palliative radiotherapy, adequate analgesia, and internal fixation of the affected long bone are different modalities of treatment in this advanced stage of disease. But the prognosis is definitely poor in this stage IV disease. Hindawi Publishing Corporation 2014 2014-08-12 /pmc/articles/PMC4145377/ /pubmed/25184068 http://dx.doi.org/10.1155/2014/636017 Text en Copyright © 2014 Anirban Das et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Das, Anirban
Pandit, Sudipta
Das, Sibes k.
Basuthakur, Sumitra
Das, Somnath
An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_full An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_fullStr An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_full_unstemmed An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_short An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity
title_sort osteolytic metastasis of humerus from an asymptomatic squamous cell carcinoma of lung: a rare clinical entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145377/
https://www.ncbi.nlm.nih.gov/pubmed/25184068
http://dx.doi.org/10.1155/2014/636017
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