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Epigallocatechingallate Inhibits Migration of Human Uveal Melanoma Cells via Downregulation of Matrix Metalloproteinase-2 Activity and ERK1/2 Pathway

The effects of epigallocatechingallate (EGCG) on the migration and expression of MMP-2 of uveal melanoma cells have not been reported. We studied this effect and relevant signaling pathways in a human uveal melanoma cell line (M17). MTT study found that EGCG did not affect the cell viability of M17...

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Detalles Bibliográficos
Autores principales: Chang, Chi-Wu, Hsieh, Yi-Hsien, Yang, Wei-En, Yang, Shun-Fa, Chen, Yueqin, Hu, Dan-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145379/
https://www.ncbi.nlm.nih.gov/pubmed/25184134
http://dx.doi.org/10.1155/2014/141582