Cargando…

Epigallocatechingallate Inhibits Migration of Human Uveal Melanoma Cells via Downregulation of Matrix Metalloproteinase-2 Activity and ERK1/2 Pathway

The effects of epigallocatechingallate (EGCG) on the migration and expression of MMP-2 of uveal melanoma cells have not been reported. We studied this effect and relevant signaling pathways in a human uveal melanoma cell line (M17). MTT study found that EGCG did not affect the cell viability of M17...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Chi-Wu, Hsieh, Yi-Hsien, Yang, Wei-En, Yang, Shun-Fa, Chen, Yueqin, Hu, Dan-Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145379/ https://www.ncbi.nlm.nih.gov/pubmed/25184134 http://dx.doi.org/10.1155/2014/141582

Ejemplares similares

Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression
por: Yang, Shih-Liang, et al.
Publicado: (2017)

CD147 and matrix-metalloproteinase-2 expression in metastatic and non-metastatic uveal melanomas
por: Lüke, Julia, et al.
Publicado: (2016)

Kaempferol Reduces Matrix Metalloproteinase-2 Expression by Down-Regulating ERK1/2 and the Activator Protein-1 Signaling Pathways in Oral Cancer Cells
por: Lin, Chiao-Wen, et al.
Publicado: (2013)

Simultaneous Inhibition of the HGF/MET and Erk1/2 Pathways Affect Uveal Melanoma Cell Growth and Migration
por: Chattopadhyay, Chandrani, et al.
Publicado: (2014)

Epigallocatechin-3-gallate inhibits migration and invasion of human renal carcinoma cells by downregulating matrix metalloproteinase-2 and matrix metalloproteinase-9
por: CHEN, SHAO-JUN, et al.
Publicado: (2016)

Casticin Inhibits A375.S2 Human Melanoma Cell Migration/Invasion through Downregulating NF-κB and Matrix Metalloproteinase-2 and -1
por: Wu, Zih-Yun, et al.
Publicado: (2016)

Tectorigenin inhibits osteosarcoma cell migration through downregulation of matrix metalloproteinases in vitro
por: Guo, Yu, et al.
Publicado: (2016)

Melatonin inhibits TPA-induced oral cancer cell migration by suppressing matrix metalloproteinase-9 activation through the histone acetylation
por: Yeh, Chia-Ming, et al.
Publicado: (2016)

YAP as oncotarget in uveal melanoma
por: Yu, Fa-Xing, et al.
Publicado: (2014)

Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression
por: Hofmann, U B, et al.
Publicado: (1999)

Overexpression of carbonic anhydrase IX induces cell motility by activating matrix metalloproteinase-9 in human oral squamous cell carcinoma cells
por: Yang, Jia-Sin, et al.
Publicado: (2017)

HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway
por: González, Mariela Natacha, et al.
Publicado: (2017)

Tomatidine Represses Invasion and Migration of Human Osteosarcoma U2OS and HOS Cells by Suppression of Presenilin 1 and c-Raf–MEK–ERK Pathway
por: Hsieh, Min-Hong, et al.
Publicado: (2020)

(−)-Epigallocatechingallate induces apoptosis in B lymphoma cells via caspase-dependent pathway and Bcl-2 family protein modulation
por: WANG, JIANGYAN, et al.
Publicado: (2015)

Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas
por: Yang, Shun-Fa, et al.
Publicado: (2014)

Downregulation of CD9 in Keratinocyte Contributes to Cell Migration via Upregulation of Matrix Metalloproteinase-9
por: Jiang, Xu-pin, et al.
Publicado: (2013)

Uveal Melanoma
por: Papastefanou, Vasilios P., et al.
Publicado: (2011)

Uveal Melanoma
por: Pfeffer, Ulrich
Publicado: (2019)

DNA Methylation and Uveal Melanoma
por: Yang, Zhi-Kun, et al.
Publicado: (2018)

Impact of Matrix Metalloproteinase-11 Gene Polymorphisms on Biochemical Recurrence and Clinicopathological Characteristics of Prostate Cancer
por: Hsieh, Chun-Yu, et al.
Publicado: (2020)

Interleukin-1β-induced matrix metalloproteinase-3 via ERK1/2 pathway to promote mesenchymal stem cell migration
por: Chang, Chun-Hao, et al.
Publicado: (2021)

Matrix metalloproteinase-2 Promotes αvβ3 Integrin-Mediated Adhesion and Migration of Human Melanoma Cells by Cleaving Fibronectin
por: Jiao, Yang, et al.
Publicado: (2012)

The Effect of Imiquimod on Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Malignant Melanoma Cell Invasion
por: Jung, Jin Young, et al.
Publicado: (2014)

Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway
por: Yeh, Liang-Tsai, et al.
Publicado: (2022)

Transforming growth factor-β1 induces matrix metalloproteinase-9 and cell migration in astrocytes: roles of ROS-dependent ERK- and JNK-NF-κB pathways
por: Hsieh, Hsi-Lung, et al.
Publicado: (2010)

Antibacterial activities of green tea crude extracts and synergistic effects of epigallocatechingallate (EGCG) with gentamicin against MDR pathogens
por: Parvez, Md. Anowar Khasru, et al.
Publicado: (2019)

Functional Roles of Matrix Metalloproteinases and Their Inhibitors in Melanoma
por: Napoli, Salvatore, et al.
Publicado: (2020)

Terminalia catappa Exerts Antimetastatic Effects on Hepatocellular Carcinoma through Transcriptional Inhibition of Matrix Metalloproteinase-9 by Modulating NF-κB and AP-1 Activity
por: Yeh, Chao-Bin, et al.
Publicado: (2012)

Downregulation of ERK signaling impairs U2OS osteosarcoma cell migration in collagen matrix by suppressing MMP9 production
por: POUDEL, BARUN, et al.
Publicado: (2014)

The Impact of Matrix Metalloproteinase-11 Polymorphisms on Colorectal Cancer Progression and Clinicopathological Characteristics
por: Huang, Hsien-Cheng, et al.
Publicado: (2022)

Corrigendum to “Terminalia catappa Exerts Antimetastatic Effects on Hepatocellular Carcinoma through Transcriptional Inhibition of Matrix Metalloproteinase-9 by Modulating NF-κB and AP-1 Activity”
por: Yeh, Chao-Bin, et al.
Publicado: (2015)

MRI of Uveal Melanoma
por: Ferreira, Teresa A., et al.
Publicado: (2019)

The biology of uveal melanoma
por: Amaro, Adriana, et al.
Publicado: (2017)

Uveal Melanoma Metastasis
por: Rossi, Ernesto, et al.
Publicado: (2021)

Uveal Melanoma Cells Utilize a Novel Route for Transendothelial Migration
por: Onken, Michael D., et al.
Publicado: (2014)

Dual Targeted Therapy with p53 siRNA and Epigallocatechingallate in a Triple Negative Breast Cancer Cell Model
por: Braicu, Cornelia, et al.
Publicado: (2015)

Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF-β1/Smad3 signaling pathway
por: Chen, Keyan, et al.
Publicado: (2018)

Tumour Suppressor Neuron Navigator 3 and Matrix Metalloproteinase 14 are Co-expressed in Most Melanomas but Downregulated in Thick Tumours
por: BUGAEVA, Olga, et al.
Publicado: (2023)

miR-652 Promotes Proliferation and Migration of Uveal Melanoma Cells by Targeting HOXA9
por: Xia, Zhaoxia, et al.
Publicado: (2019)

Downregulation of Matrix Metalloproteinases 2 and 9 is Involved in the Protective Effect of Trehalose on Spinal Cord Injury
por: Mirzaie, Masoumeh, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3aiv7vj9jicfgc9mloo207rl73