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Extracellular Membrane Vesicles Derived from 143B Osteosarcoma Cells Contain Pro-Osteoclastogenic Cargo: A Novel Communication Mechanism in Osteosarcoma Bone Microenvironment()()()()

The bone microenvironment (BME) is the main hub of all skeletal related pathological events in osteosarcoma leading to tumor induced bone destruction, and decreasing overall bone quality and bone strength. The role of extra-cellular membrane vesicles (EMVs) as mediators of intercellular communicatio...

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Detalles Bibliográficos
Autores principales: Garimella, Rama, Washington, Laurie, Isaacson, Janalee, Vallejo, Julian, Spence, Madoka, Tawfik, Ossama, Rowe, Peter, Brotto, Marco, Perez, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145399/
https://www.ncbi.nlm.nih.gov/pubmed/25180057
http://dx.doi.org/10.1016/j.tranon.2014.04.011