Cargando…
Acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry
OBJECTIVES: To look for an association between acoustic neuroma (AN) and participation in a hearing conservation programme (HCP) and also for an association between AN and possible occupational risk factors in the aluminium industry. METHODS: We conducted a case–control analysis of a population of U...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145445/ https://www.ncbi.nlm.nih.gov/pubmed/25015928 http://dx.doi.org/10.1136/oemed-2014-102094 |
_version_ | 1782332179478478848 |
---|---|
author | Taiwo, Oyebode Galusha, Deron Tessier-Sherman, Baylah Kirsche, Sharon Cantley, Linda Slade, Martin D Cullen, Mark R Donoghue, A Michael |
author_facet | Taiwo, Oyebode Galusha, Deron Tessier-Sherman, Baylah Kirsche, Sharon Cantley, Linda Slade, Martin D Cullen, Mark R Donoghue, A Michael |
author_sort | Taiwo, Oyebode |
collection | PubMed |
description | OBJECTIVES: To look for an association between acoustic neuroma (AN) and participation in a hearing conservation programme (HCP) and also for an association between AN and possible occupational risk factors in the aluminium industry. METHODS: We conducted a case–control analysis of a population of US aluminium production workers in 8 smelters and 43 other plants. Using insurance claims data, 97 cases of AN were identified between 1996 and 2009. Each was matched with four controls. Covariates included participation in a HCP, working in an aluminium smelter, working in an electrical job and hearing loss. RESULTS: In the bivariate analyses, covariates associated with AN were participation in the HCP (OR=1.72; 95% CI 1.09 to 2.69) and smelter work (OR=1.88; 95% CI 1.06 to 3.36). Electrical work was not significant (OR=1.60; 95% CI 0.65 to 3.94). Owing to high participation in the HCP in smelters, multivariate subanalyses were required. In the multivariate analyses, participation in the HCP was the only statistically significant risk factor for AN. In the multivariate analysis restricted to employees not working in a smelter, the OR was 1.81 (95% CI 1.04 to 3.17). Hearing loss, an indirect measure of in-ear noise dose, was not predictive of AN. CONCLUSIONS: Our results suggest the incidental detection of previously undiagnosed tumours in workers who participated in the company-sponsored HCP. The increased medical surveillance among this population of workers most likely introduced detection bias, leading to the identification of AN cases that would have otherwise remained undetected. |
format | Online Article Text |
id | pubmed-4145445 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-41454452014-09-02 Acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry Taiwo, Oyebode Galusha, Deron Tessier-Sherman, Baylah Kirsche, Sharon Cantley, Linda Slade, Martin D Cullen, Mark R Donoghue, A Michael Occup Environ Med Workplace OBJECTIVES: To look for an association between acoustic neuroma (AN) and participation in a hearing conservation programme (HCP) and also for an association between AN and possible occupational risk factors in the aluminium industry. METHODS: We conducted a case–control analysis of a population of US aluminium production workers in 8 smelters and 43 other plants. Using insurance claims data, 97 cases of AN were identified between 1996 and 2009. Each was matched with four controls. Covariates included participation in a HCP, working in an aluminium smelter, working in an electrical job and hearing loss. RESULTS: In the bivariate analyses, covariates associated with AN were participation in the HCP (OR=1.72; 95% CI 1.09 to 2.69) and smelter work (OR=1.88; 95% CI 1.06 to 3.36). Electrical work was not significant (OR=1.60; 95% CI 0.65 to 3.94). Owing to high participation in the HCP in smelters, multivariate subanalyses were required. In the multivariate analyses, participation in the HCP was the only statistically significant risk factor for AN. In the multivariate analysis restricted to employees not working in a smelter, the OR was 1.81 (95% CI 1.04 to 3.17). Hearing loss, an indirect measure of in-ear noise dose, was not predictive of AN. CONCLUSIONS: Our results suggest the incidental detection of previously undiagnosed tumours in workers who participated in the company-sponsored HCP. The increased medical surveillance among this population of workers most likely introduced detection bias, leading to the identification of AN cases that would have otherwise remained undetected. BMJ Publishing Group 2014-09 2014-07-11 /pmc/articles/PMC4145445/ /pubmed/25015928 http://dx.doi.org/10.1136/oemed-2014-102094 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Workplace Taiwo, Oyebode Galusha, Deron Tessier-Sherman, Baylah Kirsche, Sharon Cantley, Linda Slade, Martin D Cullen, Mark R Donoghue, A Michael Acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry |
title | Acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry |
title_full | Acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry |
title_fullStr | Acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry |
title_full_unstemmed | Acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry |
title_short | Acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry |
title_sort | acoustic neuroma: potential risk factors and audiometric surveillance in the aluminium industry |
topic | Workplace |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145445/ https://www.ncbi.nlm.nih.gov/pubmed/25015928 http://dx.doi.org/10.1136/oemed-2014-102094 |
work_keys_str_mv | AT taiwooyebode acousticneuromapotentialriskfactorsandaudiometricsurveillanceinthealuminiumindustry AT galushaderon acousticneuromapotentialriskfactorsandaudiometricsurveillanceinthealuminiumindustry AT tessiershermanbaylah acousticneuromapotentialriskfactorsandaudiometricsurveillanceinthealuminiumindustry AT kirschesharon acousticneuromapotentialriskfactorsandaudiometricsurveillanceinthealuminiumindustry AT cantleylinda acousticneuromapotentialriskfactorsandaudiometricsurveillanceinthealuminiumindustry AT slademartind acousticneuromapotentialriskfactorsandaudiometricsurveillanceinthealuminiumindustry AT cullenmarkr acousticneuromapotentialriskfactorsandaudiometricsurveillanceinthealuminiumindustry AT donoghueamichael acousticneuromapotentialriskfactorsandaudiometricsurveillanceinthealuminiumindustry |