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Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats

The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells agains...

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Autores principales: Movahedi, Ariyo, Basir, Rusliza, Rahmat, Asmah, Charaffedine, Mohammad, Othman, Fauziah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145797/
https://www.ncbi.nlm.nih.gov/pubmed/25197311
http://dx.doi.org/10.1155/2014/726724
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author Movahedi, Ariyo
Basir, Rusliza
Rahmat, Asmah
Charaffedine, Mohammad
Othman, Fauziah
author_facet Movahedi, Ariyo
Basir, Rusliza
Rahmat, Asmah
Charaffedine, Mohammad
Othman, Fauziah
author_sort Movahedi, Ariyo
collection PubMed
description The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development.
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spelling pubmed-41457972014-09-07 Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah Evid Based Complement Alternat Med Research Article The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development. Hindawi Publishing Corporation 2014 2014-08-13 /pmc/articles/PMC4145797/ /pubmed/25197311 http://dx.doi.org/10.1155/2014/726724 Text en Copyright © 2014 Ariyo Movahedi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Movahedi, Ariyo
Basir, Rusliza
Rahmat, Asmah
Charaffedine, Mohammad
Othman, Fauziah
Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
title Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
title_full Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
title_fullStr Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
title_full_unstemmed Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
title_short Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
title_sort remarkable anticancer activity of teucrium polium on hepatocellular carcinogenic rats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145797/
https://www.ncbi.nlm.nih.gov/pubmed/25197311
http://dx.doi.org/10.1155/2014/726724
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