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Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats
The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells agains...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145797/ https://www.ncbi.nlm.nih.gov/pubmed/25197311 http://dx.doi.org/10.1155/2014/726724 |
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author | Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah |
author_facet | Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah |
author_sort | Movahedi, Ariyo |
collection | PubMed |
description | The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development. |
format | Online Article Text |
id | pubmed-4145797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-41457972014-09-07 Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah Evid Based Complement Alternat Med Research Article The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development. Hindawi Publishing Corporation 2014 2014-08-13 /pmc/articles/PMC4145797/ /pubmed/25197311 http://dx.doi.org/10.1155/2014/726724 Text en Copyright © 2014 Ariyo Movahedi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title | Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_full | Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_fullStr | Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_full_unstemmed | Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_short | Remarkable Anticancer Activity of Teucrium polium on Hepatocellular Carcinogenic Rats |
title_sort | remarkable anticancer activity of teucrium polium on hepatocellular carcinogenic rats |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145797/ https://www.ncbi.nlm.nih.gov/pubmed/25197311 http://dx.doi.org/10.1155/2014/726724 |
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