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Local delivery of minocycline-loaded PEG-PLA nanoparticles for the enhanced treatment of periodontitis in dogs

BACKGROUND: Rapid local drug clearance of antimicrobials is a major drawback for the treatment of chronic periodontitis. In the study reported here, minocycline-loaded poly(ethylene glycol)-poly(lactic acid) nanoparticles were prepared and administered locally for long drug retention and enhanced tr...

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Detalles Bibliográficos
Autores principales:	Yao, Wenxin, Xu, Peicheng, Pang, Zhiqing, Zhao, Jingjing, Chai, Zhilan, Li, Xiaoxia, Li, Huan, Jiang, Menglin, Cheng, Hongbo, Zhang, Bo, Cheng, Nengneng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145825/ https://www.ncbi.nlm.nih.gov/pubmed/25170266 http://dx.doi.org/10.2147/IJN.S67521

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