Comparison of effects of anti-angiogenic agents in the zebrafish efficacy–toxicity model for translational anti-angiogenic drug discovery

BACKGROUND: Anti-angiogenic therapy in certain cancers has been associated with improved control of tumor growth and metastasis. Development of anti-angiogenic agents has, however, been saddled with higher attrition rate due to suboptimal efficacy, narrow therapeutic windows, or development of organ...

Descripción completa

Detalles Bibliográficos
Autores principales: Chimote, Geetanjali, Sreenivasan, Jayasree, Pawar, Nilambari, Subramanian, Jyothi, Sivaramakrishnan, Hariharan, Sharma, Somesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145829/
https://www.ncbi.nlm.nih.gov/pubmed/25170251
http://dx.doi.org/10.2147/DDDT.S55621

Ejemplares similares

Ejemplares similares