Diazoxide preconditioning antagonizes cytotoxicity induced by epileptic seizures★

Diazoxide, an activator of mitochondrial ATP-sensitive potassium channels, can protect neurons and astrocytes against oxidative stress and apoptosis. In this study, we established a cellular model of epilepsy by culturing hippocampal neurons in magnesium-free medium, and used this to investigate eff...

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Detalles Bibliográficos
Autores principales: Fu, Qingxi, Sun, Zhiqing, Zhang, Jinling, Gao, Naiyong, Qi, Faying, Che, Fengyuan, Ma, Guozhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Neurodegenerative Disease and Neural Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145886/
https://www.ncbi.nlm.nih.gov/pubmed/25206393
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.11.005

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