Inner ear hair cell regeneration: A look from the past to the future

Most recent studies on regeneration of inner ear hair cells focus on use of stem cells, gene therapy and neurotrophic factors. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. This suggests that cochlear hair cell regeneration is possible. The objective...

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Detalles Bibliográficos
Autores principales: Santaolalla, Francisco, Salvador, Carlos, Martínez, Agustín, Sánchez, Jose María, del Rey, Ana Sánchez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146031/
https://www.ncbi.nlm.nih.gov/pubmed/25206538
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.008
Descripción
Sumario:Most recent studies on regeneration of inner ear hair cells focus on use of stem cells, gene therapy and neurotrophic factors. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. This suggests that cochlear hair cell regeneration is possible. The objective of this paper is to review research and clinical application of inner near hair cell regeneration.

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