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Inner ear hair cell regeneration: A look from the past to the future
Most recent studies on regeneration of inner ear hair cells focus on use of stem cells, gene therapy and neurotrophic factors. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. This suggests that cochlear hair cell regeneration is possible. The objective...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146031/ https://www.ncbi.nlm.nih.gov/pubmed/25206538 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.008 |
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author | Santaolalla, Francisco Salvador, Carlos Martínez, Agustín Sánchez, Jose María del Rey, Ana Sánchez |
author_facet | Santaolalla, Francisco Salvador, Carlos Martínez, Agustín Sánchez, Jose María del Rey, Ana Sánchez |
author_sort | Santaolalla, Francisco |
collection | PubMed |
description | Most recent studies on regeneration of inner ear hair cells focus on use of stem cells, gene therapy and neurotrophic factors. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. This suggests that cochlear hair cell regeneration is possible. The objective of this paper is to review research and clinical application of inner near hair cell regeneration. |
format | Online Article Text |
id | pubmed-4146031 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41460312014-09-09 Inner ear hair cell regeneration: A look from the past to the future Santaolalla, Francisco Salvador, Carlos Martínez, Agustín Sánchez, Jose María del Rey, Ana Sánchez Neural Regen Res Review Article Most recent studies on regeneration of inner ear hair cells focus on use of stem cells, gene therapy and neurotrophic factors. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. This suggests that cochlear hair cell regeneration is possible. The objective of this paper is to review research and clinical application of inner near hair cell regeneration. Medknow Publications & Media Pvt Ltd 2013-08-25 /pmc/articles/PMC4146031/ /pubmed/25206538 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.008 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Santaolalla, Francisco Salvador, Carlos Martínez, Agustín Sánchez, Jose María del Rey, Ana Sánchez Inner ear hair cell regeneration: A look from the past to the future |
title | Inner ear hair cell regeneration: A look from the past to the future |
title_full | Inner ear hair cell regeneration: A look from the past to the future |
title_fullStr | Inner ear hair cell regeneration: A look from the past to the future |
title_full_unstemmed | Inner ear hair cell regeneration: A look from the past to the future |
title_short | Inner ear hair cell regeneration: A look from the past to the future |
title_sort | inner ear hair cell regeneration: a look from the past to the future |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146031/ https://www.ncbi.nlm.nih.gov/pubmed/25206538 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.008 |
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