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Inner ear hair cell regeneration: A look from the past to the future

Most recent studies on regeneration of inner ear hair cells focus on use of stem cells, gene therapy and neurotrophic factors. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. This suggests that cochlear hair cell regeneration is possible. The objective...

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Detalles Bibliográficos
Autores principales: Santaolalla, Francisco, Salvador, Carlos, Martínez, Agustín, Sánchez, Jose María, del Rey, Ana Sánchez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146031/
https://www.ncbi.nlm.nih.gov/pubmed/25206538
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.008
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author Santaolalla, Francisco
Salvador, Carlos
Martínez, Agustín
Sánchez, Jose María
del Rey, Ana Sánchez
author_facet Santaolalla, Francisco
Salvador, Carlos
Martínez, Agustín
Sánchez, Jose María
del Rey, Ana Sánchez
author_sort Santaolalla, Francisco
collection PubMed
description Most recent studies on regeneration of inner ear hair cells focus on use of stem cells, gene therapy and neurotrophic factors. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. This suggests that cochlear hair cell regeneration is possible. The objective of this paper is to review research and clinical application of inner near hair cell regeneration.
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spelling pubmed-41460312014-09-09 Inner ear hair cell regeneration: A look from the past to the future Santaolalla, Francisco Salvador, Carlos Martínez, Agustín Sánchez, Jose María del Rey, Ana Sánchez Neural Regen Res Review Article Most recent studies on regeneration of inner ear hair cells focus on use of stem cells, gene therapy and neurotrophic factors. Cochlear gene therapy has been successfully used in the treatment of neurosensory hearing loss. This suggests that cochlear hair cell regeneration is possible. The objective of this paper is to review research and clinical application of inner near hair cell regeneration. Medknow Publications & Media Pvt Ltd 2013-08-25 /pmc/articles/PMC4146031/ /pubmed/25206538 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.008 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Santaolalla, Francisco
Salvador, Carlos
Martínez, Agustín
Sánchez, Jose María
del Rey, Ana Sánchez
Inner ear hair cell regeneration: A look from the past to the future
title Inner ear hair cell regeneration: A look from the past to the future
title_full Inner ear hair cell regeneration: A look from the past to the future
title_fullStr Inner ear hair cell regeneration: A look from the past to the future
title_full_unstemmed Inner ear hair cell regeneration: A look from the past to the future
title_short Inner ear hair cell regeneration: A look from the past to the future
title_sort inner ear hair cell regeneration: a look from the past to the future
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146031/
https://www.ncbi.nlm.nih.gov/pubmed/25206538
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.24.008
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