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Anomalous expression of chloride transporters in the sclerosed hippocampus of mesial temporal lobe epilepsy patients

The Na(+)-K(+)-Cl(-) cotransporter 1 and K(+)-Cl(-) cotransporter 2 regulate the levels of intracellular chloride in hippocampal cells. Impaired chloride transport by these proteins is thought to be involved in the pathophysiological mechanisms of mesial temporal lobe epilepsy. Imbalance in the rela...

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Detalles Bibliográficos
Autores principales: Cai, Xiaodong, Yang, Libai, Zhou, Jueqian, Zhu, Dan, Guo, Qiang, Chen, Ziyi, Chen, Shuda, Zhou, Liemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146056/
https://www.ncbi.nlm.nih.gov/pubmed/25206700
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.06.010

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