The Olig family affects central nervous system development and disease

Neural cell differentiation and maturation is a critical step during central nervous system development. The oligodendrocyte transcription family (Olig family) is known to be an important factor in regulating neural cell differentiation. Because of this, the Olig family also affects acute and chroni...

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Autores principales: Tan, Botao, Yu, Jing, Yin, Ying, Jia, Gongwei, Jiang, Wei, Yu, Lehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146145/
https://www.ncbi.nlm.nih.gov/pubmed/25206819
http://dx.doi.org/10.4103/1673-5374.128232
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author Tan, Botao
Yu, Jing
Yin, Ying
Jia, Gongwei
Jiang, Wei
Yu, Lehua
author_facet Tan, Botao
Yu, Jing
Yin, Ying
Jia, Gongwei
Jiang, Wei
Yu, Lehua
author_sort Tan, Botao
collection PubMed
description Neural cell differentiation and maturation is a critical step during central nervous system development. The oligodendrocyte transcription family (Olig family) is known to be an important factor in regulating neural cell differentiation. Because of this, the Olig family also affects acute and chronic central nervous system diseases, including brain injury, multiple sclerosis, and even gliomas. Improved understanding about the functions of the Olig family in central nervous system development and disease will greatly aid novel breakthroughs in central nervous system diseases. This review investigates the role of the Olig family in central nervous system development and related diseases.
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spelling pubmed-41461452014-09-09 The Olig family affects central nervous system development and disease Tan, Botao Yu, Jing Yin, Ying Jia, Gongwei Jiang, Wei Yu, Lehua Neural Regen Res Review Neural cell differentiation and maturation is a critical step during central nervous system development. The oligodendrocyte transcription family (Olig family) is known to be an important factor in regulating neural cell differentiation. Because of this, the Olig family also affects acute and chronic central nervous system diseases, including brain injury, multiple sclerosis, and even gliomas. Improved understanding about the functions of the Olig family in central nervous system development and disease will greatly aid novel breakthroughs in central nervous system diseases. This review investigates the role of the Olig family in central nervous system development and related diseases. Medknow Publications & Media Pvt Ltd 2014-02-01 /pmc/articles/PMC4146145/ /pubmed/25206819 http://dx.doi.org/10.4103/1673-5374.128232 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Tan, Botao
Yu, Jing
Yin, Ying
Jia, Gongwei
Jiang, Wei
Yu, Lehua
The Olig family affects central nervous system development and disease
title The Olig family affects central nervous system development and disease
title_full The Olig family affects central nervous system development and disease
title_fullStr The Olig family affects central nervous system development and disease
title_full_unstemmed The Olig family affects central nervous system development and disease
title_short The Olig family affects central nervous system development and disease
title_sort olig family affects central nervous system development and disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146145/
https://www.ncbi.nlm.nih.gov/pubmed/25206819
http://dx.doi.org/10.4103/1673-5374.128232
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