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Fetal umbilical vein transplantation for the repair of middle cerebral artery injury
It is necessary to investigate the longitudinal tensile mechanical characteristics of the middle cerebral artery and the fetal umbilical vein prior to applying fetal umbilical vein transplantation for repair of injured middle cerebral artery. Fifteen fresh fetal umbilical vein specimens and 15 norma...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146187/ https://www.ncbi.nlm.nih.gov/pubmed/25206646 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.34.009 |
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author | Hou, Xuhui Yuan, Yi Yin, Jian Yang, Songbai Xie, Lili Wang, Shiji |
author_facet | Hou, Xuhui Yuan, Yi Yin, Jian Yang, Songbai Xie, Lili Wang, Shiji |
author_sort | Hou, Xuhui |
collection | PubMed |
description | It is necessary to investigate the longitudinal tensile mechanical characteristics of the middle cerebral artery and the fetal umbilical vein prior to applying fetal umbilical vein transplantation for repair of injured middle cerebral artery. Fifteen fresh fetal umbilical vein specimens and 15 normal human fresh cadaver middle cerebral artery specimens were collected for longitudinal tensile testing at the speed of 0.5 mm/min and at normal human temperature. The results showed that under 16.0 kPa physiological stress, the strain value of fetal umbilical vein specimens was larger, while the maximal stress and elastic modulus values were less than those of middle cerebral artery specimens. Our findings indicate that fetal umbilical vein has good elastic properties and the stress-strain curve of the fetal umbilical vein is similar to that of the middle cerebral artery. Fetal umbilical vein transplantation can, therefore, potentially repair the injured middle cerebral artery. |
format | Online Article Text |
id | pubmed-4146187 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-41461872014-09-09 Fetal umbilical vein transplantation for the repair of middle cerebral artery injury Hou, Xuhui Yuan, Yi Yin, Jian Yang, Songbai Xie, Lili Wang, Shiji Neural Regen Res Technique and Method Article: Basic Research in Neural Regeneration It is necessary to investigate the longitudinal tensile mechanical characteristics of the middle cerebral artery and the fetal umbilical vein prior to applying fetal umbilical vein transplantation for repair of injured middle cerebral artery. Fifteen fresh fetal umbilical vein specimens and 15 normal human fresh cadaver middle cerebral artery specimens were collected for longitudinal tensile testing at the speed of 0.5 mm/min and at normal human temperature. The results showed that under 16.0 kPa physiological stress, the strain value of fetal umbilical vein specimens was larger, while the maximal stress and elastic modulus values were less than those of middle cerebral artery specimens. Our findings indicate that fetal umbilical vein has good elastic properties and the stress-strain curve of the fetal umbilical vein is similar to that of the middle cerebral artery. Fetal umbilical vein transplantation can, therefore, potentially repair the injured middle cerebral artery. Medknow Publications & Media Pvt Ltd 2013-12-05 /pmc/articles/PMC4146187/ /pubmed/25206646 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.34.009 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Technique and Method Article: Basic Research in Neural Regeneration Hou, Xuhui Yuan, Yi Yin, Jian Yang, Songbai Xie, Lili Wang, Shiji Fetal umbilical vein transplantation for the repair of middle cerebral artery injury |
title | Fetal umbilical vein transplantation for the repair of middle cerebral artery injury |
title_full | Fetal umbilical vein transplantation for the repair of middle cerebral artery injury |
title_fullStr | Fetal umbilical vein transplantation for the repair of middle cerebral artery injury |
title_full_unstemmed | Fetal umbilical vein transplantation for the repair of middle cerebral artery injury |
title_short | Fetal umbilical vein transplantation for the repair of middle cerebral artery injury |
title_sort | fetal umbilical vein transplantation for the repair of middle cerebral artery injury |
topic | Technique and Method Article: Basic Research in Neural Regeneration |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146187/ https://www.ncbi.nlm.nih.gov/pubmed/25206646 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.34.009 |
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