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Fetal umbilical vein transplantation for the repair of middle cerebral artery injury

It is necessary to investigate the longitudinal tensile mechanical characteristics of the middle cerebral artery and the fetal umbilical vein prior to applying fetal umbilical vein transplantation for repair of injured middle cerebral artery. Fifteen fresh fetal umbilical vein specimens and 15 norma...

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Autores principales: Hou, Xuhui, Yuan, Yi, Yin, Jian, Yang, Songbai, Xie, Lili, Wang, Shiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146187/
https://www.ncbi.nlm.nih.gov/pubmed/25206646
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.34.009
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author Hou, Xuhui
Yuan, Yi
Yin, Jian
Yang, Songbai
Xie, Lili
Wang, Shiji
author_facet Hou, Xuhui
Yuan, Yi
Yin, Jian
Yang, Songbai
Xie, Lili
Wang, Shiji
author_sort Hou, Xuhui
collection PubMed
description It is necessary to investigate the longitudinal tensile mechanical characteristics of the middle cerebral artery and the fetal umbilical vein prior to applying fetal umbilical vein transplantation for repair of injured middle cerebral artery. Fifteen fresh fetal umbilical vein specimens and 15 normal human fresh cadaver middle cerebral artery specimens were collected for longitudinal tensile testing at the speed of 0.5 mm/min and at normal human temperature. The results showed that under 16.0 kPa physiological stress, the strain value of fetal umbilical vein specimens was larger, while the maximal stress and elastic modulus values were less than those of middle cerebral artery specimens. Our findings indicate that fetal umbilical vein has good elastic properties and the stress-strain curve of the fetal umbilical vein is similar to that of the middle cerebral artery. Fetal umbilical vein transplantation can, therefore, potentially repair the injured middle cerebral artery.
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spelling pubmed-41461872014-09-09 Fetal umbilical vein transplantation for the repair of middle cerebral artery injury Hou, Xuhui Yuan, Yi Yin, Jian Yang, Songbai Xie, Lili Wang, Shiji Neural Regen Res Technique and Method Article: Basic Research in Neural Regeneration It is necessary to investigate the longitudinal tensile mechanical characteristics of the middle cerebral artery and the fetal umbilical vein prior to applying fetal umbilical vein transplantation for repair of injured middle cerebral artery. Fifteen fresh fetal umbilical vein specimens and 15 normal human fresh cadaver middle cerebral artery specimens were collected for longitudinal tensile testing at the speed of 0.5 mm/min and at normal human temperature. The results showed that under 16.0 kPa physiological stress, the strain value of fetal umbilical vein specimens was larger, while the maximal stress and elastic modulus values were less than those of middle cerebral artery specimens. Our findings indicate that fetal umbilical vein has good elastic properties and the stress-strain curve of the fetal umbilical vein is similar to that of the middle cerebral artery. Fetal umbilical vein transplantation can, therefore, potentially repair the injured middle cerebral artery. Medknow Publications & Media Pvt Ltd 2013-12-05 /pmc/articles/PMC4146187/ /pubmed/25206646 http://dx.doi.org/10.3969/j.issn.1673-5374.2013.34.009 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technique and Method Article: Basic Research in Neural Regeneration
Hou, Xuhui
Yuan, Yi
Yin, Jian
Yang, Songbai
Xie, Lili
Wang, Shiji
Fetal umbilical vein transplantation for the repair of middle cerebral artery injury
title Fetal umbilical vein transplantation for the repair of middle cerebral artery injury
title_full Fetal umbilical vein transplantation for the repair of middle cerebral artery injury
title_fullStr Fetal umbilical vein transplantation for the repair of middle cerebral artery injury
title_full_unstemmed Fetal umbilical vein transplantation for the repair of middle cerebral artery injury
title_short Fetal umbilical vein transplantation for the repair of middle cerebral artery injury
title_sort fetal umbilical vein transplantation for the repair of middle cerebral artery injury
topic Technique and Method Article: Basic Research in Neural Regeneration
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146187/
https://www.ncbi.nlm.nih.gov/pubmed/25206646
http://dx.doi.org/10.3969/j.issn.1673-5374.2013.34.009
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