Krüppel-Like Factor 5 Mediates Proinflammatory Cytokine Expression in Lipopolysaccharide-Induced Acute Lung Injury through Upregulation of Nuclear Factor-κB Phosphorylation In Vitro and In Vivo

Acute lung injury (ALI) is associated with an inflammation-mediated process, and the transcription factor, Krüppel-like factor 5 (KLF5), might play a crucial role in inflammatory lung disease. In this study, we evaluated KLF5, reactive oxygen species (ROS), and inflammatory responses in a lipopolysa...

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Detalles Bibliográficos
Autores principales: Chen, Hsiu-Lin, Chong, Inn-Wen, Lee, Yi-Chen, Tsai, Jong-Rung, Yuan, Shyng-Shiou F., Wang, Hui-Min, Liu, Wei-Lun, Liu, Po-Len
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146351/
https://www.ncbi.nlm.nih.gov/pubmed/25197166
http://dx.doi.org/10.1155/2014/281984

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