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Androgen deprivation induces phenotypic plasticity and promotes resistance to molecular targeted therapy in a PTEN-deficient mouse model of prostate cancer

Castration-resistant prostate cancer is an incurable heterogeneous disease that is characterized by a complex multistep process involving different cellular and biochemical changes brought on by genetic and epigenetic alterations. These changes lead to the activation or overexpression of key surviva...

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Detalles Bibliográficos
Autores principales:	De Velasco, Marco A., Tanaka, Motoyoshi, Yamamoto, Yutaka, Hatanaka, Yuji, Koike, Hiroyuki, Nishio, Kazuto, Yoshikawa, Kazuhiro, Uemura, Hirotsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Original Manuscript
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146423/ https://www.ncbi.nlm.nih.gov/pubmed/24986896 http://dx.doi.org/10.1093/carcin/bgu143

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