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Portable Optical Epidural Needle-A CMOS-Based System Solution and Its Circuit Design
Epidural anesthesia is a common anesthesia method yet up to 10% of procedures fail to provide adequate analgesia. This is usually due to misinterpreting the tactile information derived from the advancing needle through the complex tissue planes. Incorrect placement also can cause dural puncture and...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146568/ https://www.ncbi.nlm.nih.gov/pubmed/25162150 http://dx.doi.org/10.1371/journal.pone.0106055 |
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author | Gong, Cihun-Siyong Alex Lin, Shih-Pin Mandell, M. Susan Tsou, Mei-Yung Chang, Yin Ting, Chien-Kun |
author_facet | Gong, Cihun-Siyong Alex Lin, Shih-Pin Mandell, M. Susan Tsou, Mei-Yung Chang, Yin Ting, Chien-Kun |
author_sort | Gong, Cihun-Siyong Alex |
collection | PubMed |
description | Epidural anesthesia is a common anesthesia method yet up to 10% of procedures fail to provide adequate analgesia. This is usually due to misinterpreting the tactile information derived from the advancing needle through the complex tissue planes. Incorrect placement also can cause dural puncture and neural injury. We developed an optic system capable of reliably identifying tissue planes surrounding the epidural space. However the new technology was too large and cumbersome for practical clinical use. We present a miniaturized version of our optic system using chip technology (first generation CMOS-based system) for logic functions. The new system was connected to an alarm that was triggered once the optic properties of the epidural were identified. The aims of this study were to test our miniaturized system in a porcine model and describe the technology to build this new clinical tool. Our system was tested in a porcine model and identified the epidural space in the lumbar, low and high thoracic regions of the spine. The new technology identified the epidural space in all but 1 of 46 attempts. Experimental results from our fabricated integrated circuit and animal study show the new tool has future clinical potential. |
format | Online Article Text |
id | pubmed-4146568 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-41465682014-08-29 Portable Optical Epidural Needle-A CMOS-Based System Solution and Its Circuit Design Gong, Cihun-Siyong Alex Lin, Shih-Pin Mandell, M. Susan Tsou, Mei-Yung Chang, Yin Ting, Chien-Kun PLoS One Research Article Epidural anesthesia is a common anesthesia method yet up to 10% of procedures fail to provide adequate analgesia. This is usually due to misinterpreting the tactile information derived from the advancing needle through the complex tissue planes. Incorrect placement also can cause dural puncture and neural injury. We developed an optic system capable of reliably identifying tissue planes surrounding the epidural space. However the new technology was too large and cumbersome for practical clinical use. We present a miniaturized version of our optic system using chip technology (first generation CMOS-based system) for logic functions. The new system was connected to an alarm that was triggered once the optic properties of the epidural were identified. The aims of this study were to test our miniaturized system in a porcine model and describe the technology to build this new clinical tool. Our system was tested in a porcine model and identified the epidural space in the lumbar, low and high thoracic regions of the spine. The new technology identified the epidural space in all but 1 of 46 attempts. Experimental results from our fabricated integrated circuit and animal study show the new tool has future clinical potential. Public Library of Science 2014-08-27 /pmc/articles/PMC4146568/ /pubmed/25162150 http://dx.doi.org/10.1371/journal.pone.0106055 Text en © 2014 Gong et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Gong, Cihun-Siyong Alex Lin, Shih-Pin Mandell, M. Susan Tsou, Mei-Yung Chang, Yin Ting, Chien-Kun Portable Optical Epidural Needle-A CMOS-Based System Solution and Its Circuit Design |
title | Portable Optical Epidural Needle-A CMOS-Based System Solution and Its Circuit Design |
title_full | Portable Optical Epidural Needle-A CMOS-Based System Solution and Its Circuit Design |
title_fullStr | Portable Optical Epidural Needle-A CMOS-Based System Solution and Its Circuit Design |
title_full_unstemmed | Portable Optical Epidural Needle-A CMOS-Based System Solution and Its Circuit Design |
title_short | Portable Optical Epidural Needle-A CMOS-Based System Solution and Its Circuit Design |
title_sort | portable optical epidural needle-a cmos-based system solution and its circuit design |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146568/ https://www.ncbi.nlm.nih.gov/pubmed/25162150 http://dx.doi.org/10.1371/journal.pone.0106055 |
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