Cargando…

Beyond Genotype: Serotonin Transporter Epigenetic Modification Predicts Human Brain Function

We examined epigenetic regulation in regards to behaviorally and clinically relevant human brain function. Specifically, we found that increased promoter methylation of the serotonin transporter gene predicted increased threat-related amygdala reactivity and decreased mRNA expression in postmortem a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nikolova, Yuliya S., Koenen, Karestan C., Galea, Sandro, Wang, Chiou-Miin, Seney, Marianne L., Sibille, Etienne, Williamson, Douglas E., Hariri, Ahmad R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146649/ https://www.ncbi.nlm.nih.gov/pubmed/25086606 http://dx.doi.org/10.1038/nn.3778

Ejemplares similares

Epigenetic modifications associated with suicide and common mood and anxiety disorders: a systematic review of the literature
por: El-Sayed, Abdulrahman M, et al.
Publicado: (2012)

Sex differences in mood disorders: perspectives from humans and rodent models
por: Seney, Marianne L, et al.
Publicado: (2014)

Ancient evolutionary origins of epigenetic regulation associated with posttraumatic stress disorder
por: Sipahi, Levent, et al.
Publicado: (2014)

Neighborhood environment, social cohesion, and epigenetic aging
por: Martin, Chantel L., et al.
Publicado: (2021)

Epigenetic predictors of all-cause mortality are associated with objective measures of neighborhood disadvantage in an urban population
por: Ward-Caviness, Cavin K., et al.
Publicado: (2020)

The Role of Genes in Defining a Molecular Biology of PTSD
por: Yehuda, Rachel, et al.
Publicado: (2011)

Sex chromosome complement regulates expression of mood-related genes
por: Seney, Marianne L, et al.
Publicado: (2013)

FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk
por: Nikolova, Yuliya S., et al.
Publicado: (2015)

Maternal immune activation epigenetically regulates hippocampal serotonin transporter levels
por: Reisinger, Sonali N., et al.
Publicado: (2016)

Neural responses to threat and reward interact to predict stress-related problem drinking: A novel protective role of the amygdala
por: Nikolova, Yuliya S, et al.
Publicado: (2012)

Kleptomania: Beyond serotonin
por: Mangot, Ajish G.
Publicado: (2014)

Epigenetic Changes of Serotonin Transporter in the Patients with Alcohol Dependence: Methylation of an Serotonin Transporter Promoter CpG Island
por: Park, Byung-Yang, et al.
Publicado: (2011)

Serotonylation: Serotonin Signaling and Epigenetics
por: Bader, Michael
Publicado: (2019)

Influence of Threat and Serotonin Transporter Genotype on Interference Effects
por: Jasinska, Agnes J., et al.
Publicado: (2012)

Behavioral lateralization of mice varying in serotonin transporter genotype
por: Stieger, Binia, et al.
Publicado: (2023)

Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond
por: Breiling, Achim, et al.
Publicado: (2015)

Epigenetic modifications and metabolic memory in diabetic retinopathy: beyond the surface
por: Liu, Dan-Dan, et al.
Publicado: (2022)

A reflection on A House in the Sky by Amanda Lindhout and Sara Corbett
por: Koenen, Karestan C.
Publicado: (2014)

Molecular Variation at the SLC6A3 Locus Predicts Lifetime Risk of PTSD in the Detroit Neighborhood Health Study
por: Chang, Shun-Chiao, et al.
Publicado: (2012)

Correction: Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms
por: Mareckova, Klara, et al.
Publicado: (2021)

Novel polygenic risk score as a translational tool linking depression-related changes in the corticolimbic transcriptome with neural face processing and anhedonic symptoms
por: Mareckova, Klara, et al.
Publicado: (2020)

The Role of Genetic Sex in Affect Regulation and Expression of GABA-Related Genes Across Species
por: Seney, Marianne L., et al.
Publicado: (2013)

RORA and posttraumatic stress trajectories: main effects and interactions with childhood physical abuse history
por: Lowe, Sarah R, et al.
Publicado: (2015)

Serotonin transporter genotype, morning cortisol and subsequent depression in adolescents
por: Goodyer, Ian M., et al.
Publicado: (2009)

Association between psychological resilience and cognitive function in older adults: effect modification by inflammatory status
por: Jung, Sun Jae, et al.
Publicado: (2021)

Gene Expression and Methylation Signatures of MAN2C1 are Associated with PTSD
por: Uddin, Monica, et al.
Publicado: (2011)

Exploring the Impact of BDNF Val66Met Genotype on Serotonin Transporter and Serotonin-1A Receptor Binding
por: Kraus, Christoph, et al.
Publicado: (2014)

Serotonin Transporter Genotype Modulates Social Reward and Punishment in Rhesus Macaques
por: Watson, Karli K., et al.
Publicado: (2009)

Serotonin Transporter Genotype (5-HTTLPR) Predicts Utilitarian Moral Judgments
por: Marsh, Abigail A., et al.
Publicado: (2011)

Shifting priorities: highly conserved behavioral and brain network adaptations to chronic stress across species
por: Nikolova, Yuliya S., et al.
Publicado: (2018)

Correction: Exploring the Impact of BDNF Val66Met Genotype on Serotonin Transporter and Serotonin-1A Receptor Binding
Publicado: (2014)

Pathophysiology of the Serotonin System in the Nervous System and Beyond
por: De Deurwaerdère, Philippe, et al.
Publicado: (2022)

Association between Genotype of the Serotonin Transporter-Linked Polymorphic Region of the Serotonin Transporter Gene and Age of Onset of Methamphetamine Use: a Preliminary Analysis
por: Johnson, Bankole A., et al.
Publicado: (2010)

Effects of Genotype and Child Abuse on DNA Methylation and Gene Expression at the Serotonin Transporter
por: Vijayendran, Meeshanthini, et al.
Publicado: (2012)

Latent Class Analysis of Antisocial Behavior: Interaction of Serotonin Transporter Genotype and Maltreatment
por: Li, James J., et al.
Publicado: (2010)

Consequences of Serotonin Transporter Genotype and Early Adversity on Behavioral Profile – Pathology or Adaptation?
por: Heiming, Rebecca S., et al.
Publicado: (2010)

Affective Neural Responses Modulated by Serotonin Transporter Genotype in Clinical Anxiety and Depression
por: Oathes, Desmond J., et al.
Publicado: (2015)

Divergent responses of the amygdala and ventral striatum predict stress-related problem drinking in young adults: Possible differential markers of affective and impulsive pathways of risk for alcohol use disorder
por: Nikolova, Yuliya S., et al.
Publicado: (2015)

Serotonin and serotonin transporter levels in autistic children
por: Abdulamir, Haidar A., et al.
Publicado: (2018)

Effect of Acute Stressor and Serotonin Transporter Genotype on Amygdala First Wave Transcriptome in Mice
por: Hohoff, Christa, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_04qbvv4q3emh5tg20l4antqcla