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A systems biology approach identified different regulatory networks targeted by KSHV miR-K12-11 in B cells and endothelial cells

BACKGROUND: Kaposi’s sarcoma associated herpes virus (KSHV) is associated with tumors of endothelial and lymphoid origin. During latent infection, KSHV expresses miR-K12-11, an ortholog of the human tumor gene hsa-miR-155. Both gene products are microRNAs (miRNAs), which are important post-transcrip...

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Detalles Bibliográficos
Autores principales: Yang, Yajie, Boss, Isaac W, McIntyre, Lauren M, Renne, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147158/
https://www.ncbi.nlm.nih.gov/pubmed/25106478
http://dx.doi.org/10.1186/1471-2164-15-668